American singer and actress Whitney Houston has died in Los Angeles at the age of 48.
Police said she died in her room at the Beverly Hilton Hotel, where she had been staying as a guest.
Houston was one of the most celebrated female singers of all time, with hits including I Will Always Love You and Saving All My Love For You.
But her later career was overshadowed by substance abuse and her turbulent marriage to singer Bobby Brown.
Ms Houston died on the eve of the Grammy Awards in Los Angeles. She had been due to attend a pre-awards party in the Beverly Hilton Hotel organised by her long-time mentor and record industry executive Clive Davis on Saturday evening.
The hotel was already teeming with reporters and celebrities when police received an emergency call from hotel security at 15.43 local time (23:43 GMT), Beverly Hills police spokesman Mark Rosen told the BBC.
Police were despatched, but paramedics, already at the hotel because of the party, attempted to resuscitate her, without success. She was pronounced dead at 15:55.
Mr Rosen said Ms Houston's entourage - comprising family members, friends and co-workers - had taken over much of the fourth floor of the hotel.
"There were a number of people on scene who were able to positively identify Ms Houston for us," he said, adding that her next of kin have been informed of her death.
He said police investigators were at the scene trying to determine the cause of her death, but said there were "no obvious signs of criminal intent".
'Finest voice'
Houston's background was steeped in soul and gospel music.
Her mother was gospel singer Cissy Houston, she was cousin to singer Dionne Warwick and goddaughter to Aretha Franklin.
"I just can't talk about it now," Ms Franklin said in a short statement. "It's so stunning and unbelievable. I couldn't believe what I was reading coming across the TV screen."
Having grown up in New Jersey, Houston began singing in church and then in the night clubs of New York, and was a model before being signed by Arista Records.
At the height of her career in the 1980s and 90s she won many awards and enjoyed several number one singles and albums.
Artists from Mariah Carey to Christina Aguilera have tried to emulate her bravura performances, but none of them were as good as the original, music critic Paul Gambaccini told the BBC.
Houston also enjoyed success acting in blockbuster films such as The Bodyguard and Waiting to Exhale.
In recent years drug use took its toll on the star and her voice - once acknowledged as one of the finest in pop music - was badly damaged.
"She did have it all, but the record is there of the decline into drug use and the damage done from drug use," said Gambaccini.
Her marriage to Brown, with whom she had a daughter, Bobbi Kristina, ended in divorce in 2007. The marriage had been a tempestuous one, with allegations of domestic abuse.
"The biggest devil is me. I'm either my best friend or my worst enemy,'' Houston told ABC's Diane Sawyer in a 2002 interview.
Correspondents say Houston's death will undoubtedly overshadow the music industry's Grammy Awards.
Neil Portnow, president of the Recording Academy, which runs the awards, told Reuters news agency they were working on ways of paying tribute to the singer.
Civil rights activist Rev Al Sharpton said that on the morning of the Grammys, "the world should pause and pray for the memory of a gifted songbird".
Country singer Dolly Parton - who wrote one one of her most memorable hits, I Will Always Love You - said in a statement: "Mine is only one of the millions of hearts broken over the death of Whitney Houston."
"I will always be grateful and in awe of the wonderful performance she did on my song, and I can truly say from the bottom of my heart, 'Whitney, I will always love you. You will be missed'."
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